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Had Tubal Ligation for Years and Failed ICSI Elsewhere – Successfully Conceived on the First Try with Dr. Ton


25 March 2025
Success Stories

Had Tubal Ligation for Years and Multiple Failed ICSI Transfers Elsewhere—Found Success on the First Attempt with Dr. Ton at Beyond IVF!

A 37-Year-Old Woman Who Had Tubal Ligation for Years—After Multiple Failed ICSI Attempts Elsewhere, Found Success on the First Try with Dr. Ton at Beyond IVF!

This case involves a 37-year-old woman who had undergone tubal ligation after having her last child. However, she recently wished to have another baby. Instead of undergoing tubal reversal, which has a lower chance of success through natural conception, she opted for assisted reproductive technology (ART) and initially pursued ICSI at another fertility clinic. Despite multiple embryo transfers, none were successful. There was one instance where she conceived but unfortunately experienced a miscarriage.

Determined to increase her chances of success, she sought treatment at a clinic with higher success rates and came across Beyond IVF, where she found successful cases similar to hers. She decided to consult Dr. PoonSak (Dr. Ton), bringing along her previous medical records for assessment and a personalized treatment plan.

Since her last treatment was over a year ago, Dr. Ton recommended a comprehensive evaluation for both partners to identify the root cause of their infertility struggles. While the woman’s health was normal, her husband’s sperm quality was suboptimal, which could have contributed to the limited number of viable embryos and their poor developmental potential after transfer. Dr. Ton reassured her that ICSI was still a viable option, but this time, preimplantation genetic screening (NGS) would be necessary before embryo transfer. The previous clinic had not performed NGS, which might have led to the miscarriage due to chromosomal abnormalities.

Once her menstrual cycle started, she began ovarian stimulation and underwent egg retrieval. Out of 23 retrieved eggs, 5 developed into blastocysts (the most viable stage at day 5). As advised, she proceeded with NGS screening, and the results revealed that only one embryo was chromosomally normal (No Aneuploidy Detected), while the remaining four had chromosomal abnormalities (Aneuploidy Detected).

Before proceeding with the transfer, Dr. Ton recommended freezing the embryo and delaying the transfer to allow time for optimal uterine preparation. He advised against a fresh transfer, suggesting a frozen embryo transfer (FET) instead, allowing six months for uterine recovery to enhance implantation success.

After completing the preparation phase, she underwent FET with her only viable embryo. The results? A successful pregnancy! She expressed immense gratitude, realizing that if she had continued trying naturally, she might have faced repeated miscarriages due to undiagnosed chromosomal issues. Without the NGS screening, she would never have known that only one embryo out of 23 was truly viable.

Treatment Method: ICSI (Intracytoplasmic Sperm Injection)
Additional Techniques Used:

  • ICSI: A specialized technique that injects sperm directly into the egg to enhance fertilization rates.

  • NGS (Next-Generation Sequencing): Genetic screening to detect chromosomal abnormalities in embryos.

Patient’s Testimonial:
"Thank you so much, Dr. Ton, for making our dream of having another baby come true! Beyond IVF is an amazing fertility center that truly cares about every detail of the treatment. The entire team, from nurses to staff, was incredibly supportive throughout the whole process—from our first consultation to the successful pregnancy. Highly recommended!


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The Biological Clock

This tool indicates:

  • Natural conception per month if you have no fertility issues
  • IVF success rate at the same age
  • When to seek help after months of unsuccessful attempts

If you are concerned at any stage – we recommend booking a doctor appointment or a free nurse consultation. The sooner you make a plan the better your chances in the long term.

When to seek advice early

  • If you have polycystic ovaries, endometriosis, or have been through a cancer diagnosis; we recommend you get in touch quickly so we can talk you through all your options and give you the greatest possible chance of success.
  • If you’re a single woman considering motherhood in the future; it’s best to approach us early and consider egg freezing as this can be an option for you while you have a higher ovarian reserve and healthier eggs.
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Being overweight or underweight can reduce fertility, so it is important to keep your body weight within the normal healthy range.

Body Mass Index (BMI) is an indication of your body weight and can be calculated by dividing weight by height. You should aim for a BMI of between 20 and 25, as this will optimise your chances of conception.

Woman’s BMI below 19

Even in these modern times, nature knows best. If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

Being underweight

If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

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This can reduce fertility by 50%. Pregnancy for women with a 30+ BMI is often associated with problems such as maternal diabetes, high blood pressure, big babies and increased risk of caesarean section.

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