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13 March 2025

Twins at 40 and a Dream Fulfilled

13 March 2025
Success Stories

Twins at 40 and a Dream Fulfilled

At 40 years of age, Khun Jarumas fulfilled her dream of having twins.

After struggling to conceive naturally for years and with concern creeping into her mind around her age, she feared the worst, as post-40 was, in her mind, the end of her fertile years. As a last ditch effort, she decided to consult Dr. Ton, who reassured her that IVF/ICSI had helped other couples her age (or older) conceive despite certain pre-existing conditions (age included).

With essentially nothing left to lose, she decided to start the IVF process immediately during her next menstrual cycle, receiving 10 days of ovarian stimulation. Dr. Ton monitored her progress through ultrasounds to assess follicle development, then proceeded with egg retrieval with the embryos cultured to the blastocyst stage.

Due to the patient’s age, Dr. Ton was very adamant about chromosomal testing of the embryos, which could increase the likelihood of chromosomal abnormalities, such as Down syndrome. Post-chromosomal testing resulted in two healthy embryos, and the patient, hoping for twins, discussed the possibility with Dr. Ton about the possibility of implanting both embryos together. After an evaluation of her health and a long discussion of the future risks involved in carrying twins, Dr. Ton agreed to her request and after 14 days post-transfer, a home pregnancy test revealed two lines.

The patient promptly scheduled an appointment with Dr. Ton for an hCG test, which confirmed high hormone levels, confirming the results of her home pregnancy test. Three days later, another surprise awaited her, as an ultrasound revealed two gestational sacs, and Dr. Ton confirmed that the pregnancy was indeed twins!

Assisted Reproductive Technologies Utilized

  • ICSI (Intracytoplasmic Sperm Injection)

  • PGS-NGS (genetic screening for embryo chromosomal abnormalities)

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The Biological Clock

This tool indicates:

  • Natural conception per month if you have no fertility issues
  • IVF success rate at the same age
  • When to seek help after months of unsuccessful attempts

If you are concerned at any stage – we recommend booking a doctor appointment or a free nurse consultation. The sooner you make a plan the better your chances in the long term.

When to seek advice early
  • If you have polycystic ovaries, endometriosis, or have been through a cancer diagnosis; we recommend you get in touch quickly so we can talk you through all your options and give you the greatest possible chance of success.
  • If you’re a single woman considering motherhood in the future; it’s best to approach us early and consider egg freezing as this can be an option for you while you have a higher ovarian reserve and healthier eggs.
Set your age and the months you’ve been trying to conceive
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Your chance of having a baby per month for fertile couples
Your chance of having a baby per IVF cycle (if experiencing infertility)

Body Mass Index calculator

Being overweight or underweight can reduce fertility, so it is important to keep your body weight within the normal healthy range.

Body Mass Index (BMI) is an indication of your body weight and can be calculated by dividing weight by height. You should aim for a BMI of between 20 and 25, as this will optimise your chances of conception.

Woman’s BMI below 19

Even in these modern times, nature knows best. If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

Being underweight

If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

BMI’s greater than 30

This can reduce fertility by 50%. Pregnancy for women with a 30+ BMI is often associated with problems such as maternal diabetes, high blood pressure, big babies and increased risk of caesarean section.

Add your height and weight to calculate your BMI
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