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Twin Pregnancy, a New Record for a 47-Year-Old Mother, ICSI with Dr. Phunsak at Beyond IVF


24 March 2025
Success Stories

สติถิใหม่คุณแม่วัย 47 ปี ท้องแฝด สำเร็จด้วยวิธี ICSI โดยหมอต้น พูนศักดิ์ Beyond IVF

This client was 47 years old, a record holder at Beyond IVF, who became successfully pregnant after ICSI with Dr. Ton, and with twins!

The client had tried for over 10 years to become pregnant but was not successful. She explored assisted reproductive technologies and attempted intrauterine insemination (IUI) twice, unsuccessfully. She tried ICSI once and her embryos only made it to the third day (cleavage stage) and were transferred into the uterus, but it was also unsuccessful. That’s when the client decided to try a different place for treatment.

The client participated in the seminar held by Beyond IVF to provide information to those experiencing infertility who were looking for treatment options and was chosen for a private consultation with Dr. Ton. After the consultation, the doctor recommended both partners to prepare their bodies to balance their hormones to facilitate the next ICSI cycle.

After one year the client returned to Dr. Ton to begin the ICSI process, after spending the year following Dr. Ton’s advice on becoming healthy and preparing for treatment (a technique specific to Beyond IVF). When both partners’ hormones were measured, they were found to be in the normal range, ready for treatment.

After 10 days of ovarian stimulation, Dr. Ton scheduled the client for an ultrasound to monitor the ovaries. There were 10 eggs measuring 18-20 mm. Dr. Ton scheduled egg collection immediately as 10 is considered a significant number of eggs for the client’s age.

Once fertilized, five embryos made it to the blastocyst stage at five days. The client was delighted and believed the embryos made it to day 5 because of Dr. Ton’s recommendations and his special treatment techniques.

Dr. Ton recommended the embryos undergo NGS to increase the chances of a successful pregnant as the method will screen out any embryos with chromosomal abnormalities and any low-quality embryos.

After the screening two high-quality embryos remained and Dr. Ton recommended transferring both (medical reason). The client was impressed that Dr. Ton consulted with the client regarding the transfer and there was no coercion or rushing.

Before the transfer, Dr. Ton designed a treatment technique specific to the client to adjust her hormone levels and her uterine lining to support the embryo transfer and encourage implantation.

Fifteen days after the transfer Dr. Ton scheduled the client to come in to check her hCG levels. Her hCG was 6194.18 mIU/mL, a confirmation of pregnancy! To be sure Dr. Ton scheduled the client for an ultrasound after three days to look for the yolk sac.

It was good news for the family and the doctor when the ultrasound showed two yolk sacs! “It’s twins,” confirmed Dr. Ton.

Treatment: ICSI

Additional Techniques: Intracytoplasmic sperm injection (ICSI) and next-generation sequencing (NGS)

Client’s Review: I am so happy! Dr. Ton is very skilled. I didn’t imagine we would see two yolk sacs and be pregnant with twins. Just one would have been a dream come true. Beyond IVF is fantastic, everyone is so lovely, and Dr. Ton is very talented.


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The Biological Clock

This tool indicates:

  • Natural conception per month if you have no fertility issues
  • IVF success rate at the same age
  • When to seek help after months of unsuccessful attempts

If you are concerned at any stage – we recommend booking a doctor appointment or a free nurse consultation. The sooner you make a plan the better your chances in the long term.

When to seek advice early

  • If you have polycystic ovaries, endometriosis, or have been through a cancer diagnosis; we recommend you get in touch quickly so we can talk you through all your options and give you the greatest possible chance of success.
  • If you’re a single woman considering motherhood in the future; it’s best to approach us early and consider egg freezing as this can be an option for you while you have a higher ovarian reserve and healthier eggs.
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Body Mass Index calculator

Being overweight or underweight can reduce fertility, so it is important to keep your body weight within the normal healthy range.

Body Mass Index (BMI) is an indication of your body weight and can be calculated by dividing weight by height. You should aim for a BMI of between 20 and 25, as this will optimise your chances of conception.

Woman’s BMI below 19

Even in these modern times, nature knows best. If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

Being underweight

If a woman's BMI falls below 19, the body senses famine and ovulation is switched off to prevent the risk of having a baby with malnutrition. Excessive exercise can reduce body fat and increase muscle mass to a point where periods cease for the same reason. Risk of miscarriage is also increased in women with a low BMI.

BMI’s greater than 30

This can reduce fertility by 50%. Pregnancy for women with a 30+ BMI is often associated with problems such as maternal diabetes, high blood pressure, big babies and increased risk of caesarean section.

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